The 2022 edition of ‘The Clash’ is completely unrecognizable from its predecessors as NASCAR tries something truly new to unofficially kick off the new season.
The event has always taken place at Daytona International Speedway since it began in 1979. In 2021, NASCAR moved the race from the Daytona oval to the infield road course for the very first time. But this year, the exhibition race heads to the other side of the country and into the Los Angeles Memorial Coliseum.
The race will be the first to take place inside a multi-purpose sports stadium since the 1956 Cup Series race at Soldier Field, which was won by Fireball Roberts.
The 2022 Clash, scheduled for February 6th on FOX, will feature all 36 chartered teams with 23 making the 150-lap main event (via heat races).
| Entry | Car No. | Driver | Team | Crew Chief | Manufacturer |
| 1 | 1 | Ross Chastain | TrackHouse Racing Team | Phil Surgen | Chevrolet |
| 2 | 2 | Austin Cindric | Team Penske | Jeremy Bullins | Ford |
| 3 | 3 | Austin Dillon | Richard Childress Racing | Justin Alexander | Chevrolet |
| 4 | 4 | Kevin Harvick | Stewart-Haas Racing | Rodney Childers | Ford |
| 5 | 5 | Kyle Larson | Hendrick Motorsports | Cliff Daniels | Chevrolet |
| 6 | 6 | Brad Keselowski | Roush Fenway Keselowski Racing | Matt McCall | Ford |
| 7 | 7 | Corey LaJoie | Spire Motorsports | Ryan Sparks | Chevrolet |
| 8 | 8 | Tyler Reddick | Richard Childress Racing | Randall Burnett | Chevrolet |
| 9 | 9 | Chase Elliott | Hendrick Motorsports | Alan Gustafson | Chevrolet |
| 10 | 10 | Aric Almirola | Stewart-Haas Racing | Drew Blickensderfer | Ford |
| 11 | 11 | Denny Hamlin | Joe Gibbs Racing | Chris Gabehart | Toyota |
| 12 | 12 | Ryan Blaney | Team Penske | Jonathan Hassler | Ford |
| 13 | 14 | Chase Briscoe | Stewart-Haas Racing | Johnny Klausmeier | Ford |
| 14 | 15 | Ryan Preece | Rick Ware Racing | Jason Houghtaling | Ford |
| 15 | 16 | AJ Allmendinger | Kaulig Racing | Matt Swiderski | Chevrolet |
| 16 | 17 | Chris Buescher | Roush Fenway Keselowski Racing | Scott Graves | Ford |
| 17 | 18 | Kyle Busch | Joe Gibbs Racing | Seth Chavka | Toyota |
| 18 | 19 | Martin Truex Jr. | Joe Gibbs Racing | James Small | Toyota |
| 19 | 20 | Christopher Bell | Joe Gibbs Racing | Adam Stevens | Toyota |
| 20 | 21 | Harrison Burton | Wood Brothers Racing | Brian Wilson | Ford |
| 21 | 22 | Joey Logano | Team Penske | Paul Wolfe | Ford |
| 22 | 23 | Bubba Wallace | 23XI Racing | Bootie Barker | Toyota |
| 23 | 24 | William Byron | Hendrick Motorsports | Ryan Fugle | Chevrolet |
| 24 | 31 | Justin Haley | Kaulig Racing | Trent Owens | Chevrolet |
| 25 | 34 | Michael McDowell | Front Row Motorsports | Blake Harris | Ford |
| 26 | 38 | Todd Gilliland | Front Row Motorsports | Seth Barbour | Ford |
| 27 | 41 | Cole Custer | Stewart-Haas Racing | Mike Shiplett | Ford |
| 28 | 42 | Ty Dillon | Petty GMS Racing | Jerame Donley | Chevrolet |
| 29 | 43 | Erik Jones | Petty GMS Racing | Dave Elenz | Chevrolet |
| 30 | 45 | Kurt Busch | 23XI Racing | Billy Scott | Toyota |
| 31 | 47 | Ricky Stenhouse Jr. | JTG Daugherty Racing | Brian Pattie | Chevrolet |
| 32 | 48 | Alex Bowman | Hendrick Motorsports | Greg Ives | Chevrolet |
| 33 | 51 | Cody Ware | Rick Ware Racing | Billy Plourde | Ford |
| 34 | 77 | Landon Cassill | Spire Motorsports | Kevin Bellicourt | Chevrolet |
| 35 | 78 | BJ McLeod | Live Fast Motorsports | Lee Leslie | Ford |
| 36 | 99 | Daniel Suarez | TrackHouse Racing Team | Travis Mack | Chevrolet |