The session follows Thursday’s twin 150-mile Duel races were the starting lineup was officially set for the 500.
34 of the 40 cars in the field put down a time in practice Friday. There were no incidents, but several close calls as drivers tried to learn more about the new car in the draft.
| Pos. | No. | Driver | Manufacturer | Best Speed (mph) |
| 1 | 34 | Michael McDowell | Ford | 192.678 |
| 2 | 38 | Todd Gilliland | Ford | 192.361 |
| 3 | 15 | David Ragan | Ford | 192.275 |
| 4 | 17 | Chris Buescher | Ford | 191.665 |
| 5 | 6 | Brad Keselowski | Ford | 191.661 |
| 6 | 51 | Cody Ware | Ford | 191.550 |
| 7 | 23 | Bubba Wallace | Toyota | 190.662 |
| 8 | 14 | Chase Briscoe | Ford | 190.504 |
| 9 | 10 | Aric Almirola | Ford | 190.468 |
| 10 | 62 | Noah Gragson | Chevrolet | 190.432 |
| 11 | 4 | Kevin Harvick | Ford | 190.388 |
| 12 | 41 | Cole Custer | Ford | 190.303 |
| 13 | 42 | Ty Dillon | Chevrolet | 190.247 |
| 14 | 47 | Ricky Stenhouse Jr. | Chevrolet | 190.223 |
| 15 | 43 | Erik Jones | Chevrolet | 190.223 |
| 16 | 77 | Landon Cassill | Chevrolet | 190.219 |
| 17 | 7 | Corey LaJoie | Chevrolet | 190.174 |
| 18 | 99 | Daniel Suarez | Chevrolet | 190.114 |
| 19 | 3 | Austin Dillon | Chevrolet | 190.090 |
| 20 | 1 | Ross Chastain | Chevrolet | 190.026 |
| 21 | 8 | Tyler Reddick | Chevrolet | 190.022 |
| 22 | 5 | Kyle Larson | Chevrolet | 189.266 |
| 23 | 9 | Chase Elliott | Chevrolet | 189.235 |
| 24 | 48 | Alex Bowman | Chevrolet | 189.191 |
| 25 | 18 | Kyle Busch | Toyota | 188.996 |
| 26 | 24 | William Byron | Chevrolet | 188.961 |
| 27 | 19 | Martin Truex Jr. | Toyota | 188.826 |
| 28 | 20 | Christopher Bell | Toyota | 188.806 |
| 29 | 11 | Denny Hamlin | Toyota | 188.806 |
| 30 | 2 | Austin Cindric | Ford | 188.584 |
| 31 | 50 | Kaz Grala | Chevrolet | 184.835 |
| 32 | 12 | Ryan Blaney | Ford | 182.146 |
| 33 | 22 | Joey Logano | Ford | 181.745 |
| 34 | 45 | Kurt Busch | Toyota | 180.752 |